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DC Field | Value | Language |
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dc.contributor.author | Withawat Vuthiwong | en_US |
dc.contributor.author | Anirut Watcharawipha | en_US |
dc.contributor.author | Bongkot Jia- Mahasap | en_US |
dc.contributor.author | Wannapha Nobnop | en_US |
dc.contributor.author | Imjai Chitapanarux | en_US |
dc.date.accessioned | 2022-10-16T07:24:53Z | - |
dc.date.available | 2022-10-16T07:24:53Z | - |
dc.date.issued | 2021-01-01 | en_US |
dc.identifier.issn | 14671131 | en_US |
dc.identifier.issn | 14603969 | en_US |
dc.identifier.other | 2-s2.0-85104840569 | en_US |
dc.identifier.other | 10.1017/S1460396921000339 | en_US |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85104840569&origin=inward | en_US |
dc.identifier.uri | http://cmuir.cmu.ac.th/jspui/handle/6653943832/77228 | - |
dc.description.abstract | Purpose: We reported the clinical and radiological outcome of an aggressive dural arteriovenous fistula (DAVF) after combined glue embolization and hypofractionated helical TomoTherapy (Hypo-HT). Materials and methods: Eleven patients whose radiological examinations are consistent with aggressive DAVF were treated with combined glue embolization and Hypo-HT 30-36 Gy in 5-6 fractions. The dosimetric analysis, clinical response and radiological imaging obliteration rate by magnetic resonance angiography or computed tomography angiography were investigated. Results: There were eight males and three females with a male and female ratio of 2·67. The mean age was 51·2 years old (range 37-69). Anatomical imaging sites of disease included transverse-sigmoid sinuses (n = 7), superior sagittal sinus (n = 3) and tentorium cerebelli (n = 1). The mean pitch and MF of treatment plans were 0·273 ± 0·032 and 1·70 ± 0·31, respectively. The average size of PTV were 15·39 ± 7·74 cc whereas the R eff,PTV was 1·50 ± 0·25 cm. The average Dmax and Dmin were 37·52 ± 3·34 and 31·77 ± 2·64 Gy, respectively. HI, CI and CI50 were 0·16 ± 0·06, 1·80 ± 0·56 and 7·85 ± 4·16, respectively. The R eff,Rx and Reff,50%Rx were 1·80 ± 0·24 and 2·90 ± 0·45 cm, respectively. The Reff between 50%Rx and 100%Rx was 1·10 ± 0·28 cm on average. With a mean follow up of 28·5 months (range 9-48), the complete recovery of symptoms was found in 72·7 % (eight patients) within 2-12 months after completion Hypo-HT. Partial recovery was reported in 18·2% (two patients). No clinical response was found in 9·1% (one patient). The total radiographic obliteration rate was 27·3% (three patients), subtotal obliteration was 27·3% (three patients) and partial obliteration was 45·4% (five patients). Conclusions: Satisfactory clinical response of aggressive DAVF was found in all treated patients by combining glue embolization and Hypo-HT. All dosimetric parameters were acceptable. We still need an extended follow up time to assess further radiographic obliteration rate and late side effects of the treatment. | en_US |
dc.subject | Medicine | en_US |
dc.title | Clinical and radiological response of aggressive dural arteriovenous fistula after combined glue embolization and hypofractionated helical TomoTherapy | en_US |
dc.type | Journal | en_US |
article.title.sourcetitle | Journal of Radiotherapy in Practice | en_US |
article.stream.affiliations | Chiang Mai University | en_US |
Appears in Collections: | CMUL: Journal Articles |
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